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Michael Papamichail Selected Research

invariant chain (Ii-Key)

1/2016Unraveling the role of preexisting immunity in prostate cancer patients vaccinated with a HER-2/neu hybrid peptide.
9/2015A pilot study in prostate cancer patients treated with the AE37 Ii-key-HER-2/neu polypeptide vaccine suggests that HLA-A*24 and HLA-DRB1*11 alleles may be prognostic and predictive biomarkers for clinical benefit.
11/2014AE37 peptide vaccination in prostate cancer: identification of biomarkers in the context of prognosis and prediction.
7/2010Results from a phase I clinical study of the novel Ii-Key/HER-2/neu(776-790) hybrid peptide vaccine in patients with prostate cancer.
5/2007Ii-Key/HER-2/neu(776-790) hybrid peptides induce more effective immunological responses over the native peptide in lymphocyte cultures from patients with HER-2/neu+ tumors.

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Michael Papamichail Research Topics

Disease

40Neoplasms (Cancer)
10/2018 - 01/2002
10Breast Neoplasms (Breast Cancer)
06/2020 - 07/2003
8Prostatic Neoplasms (Prostate Cancer)
07/2016 - 12/2003
2Hypersensitivity (Allergy)
09/2015 - 11/2014
2Melanoma (Melanoma, Malignant)
01/2014 - 01/2002
2Carcinoma (Carcinomatosis)
04/2010 - 03/2010
2Anterior Wall Myocardial Infarction
03/2007 - 07/2005
2Ovarian Neoplasms (Ovarian Cancer)
03/2004 - 04/2002
1Colorectal Neoplasms (Colorectal Cancer)
04/2013
1Azoospermia
09/2011
1Neoplasm Metastasis (Metastasis)
03/2011
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
12/2010
1Disease Progression
05/2007
1Ventricular Flutter
03/2007
1Ventricular Tachycardia
03/2007
1Cicatrix (Scar)
07/2005
1Hepatitis B
03/2004
1Virus Diseases (Viral Diseases)
03/2004
1Thyroid Diseases (Thyroid Disease)
01/2004
1Graves Disease (Basedow Disease)
01/2004
1Nodular Goiter
01/2004
1Thyroiditis
01/2004
1Adenocarcinoma
01/2002
1Pancreatic Neoplasms (Pancreatic Cancer)
01/2002

Drug/Important Bio-Agent (IBA)

21VaccinesIBA
06/2020 - 01/2002
19Peptides (Polypeptides)IBA
06/2020 - 04/2002
11EpitopesIBA
01/2016 - 01/2002
9AntigensIBA
10/2018 - 04/2002
6Biomarkers (Surrogate Marker)IBA
09/2015 - 03/2004
6Proteins (Proteins, Gene)FDA Link
11/2011 - 01/2002
5Protein Subunit VaccinesIBA
06/2020 - 05/2007
5Cancer VaccinesIBA
10/2018 - 01/2014
5AE37 vaccineIBA
07/2016 - 07/2010
5invariant chain (Ii-Key)IBA
01/2016 - 05/2007
5Monoclonal AntibodiesIBA
03/2009 - 08/2003
4CytokinesIBA
01/2009 - 01/2004
4Oncogene Proteins (Oncogene Protein)IBA
07/2008 - 12/2003
3Neoplasm Antigens (Tumor Antigens)IBA
01/2016 - 03/2009
3Trastuzumab (Herceptin)FDA Link
01/2014 - 03/2004
3Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
07/2010 - 05/2003
3Interleukin-18 (Interleukin 18)IBA
03/2005 - 05/2003
3Interleukin-12 (IL 12)IBA
03/2005 - 05/2003
2HLA-DRB1 Chains (HLA DRB1)IBA
07/2016 - 09/2015
2HLA-A Antigens (HLA-A)IBA
09/2015 - 11/2004
2Interferon-gamma (Interferon, gamma)IBA
11/2014 - 05/2003
2AntibodiesIBA
01/2014 - 03/2004
2Interleukin-15 (Interleukin 15)IBA
03/2011 - 03/2005
2HLA-A*02:01 antigenIBA
05/2010 - 11/2004
2Cell ExtractsIBA
11/2004 - 04/2002
2AcidsIBA
11/2004 - 04/2002
1InterferonsIBA
09/2015
1Prostate-Specific Antigen (Semenogelase)IBA
04/2015
1Transforming Growth Factor beta (TGF-beta)IBA
11/2014
1VemurafenibIBA
01/2014
1Calcibiotic Root Canal SealerIBA
04/2013
1Pharmaceutical PreparationsIBA
12/2011
1Aligeron (AS 2)IBA
09/2011
1Transcription Factors (Transcription Factor)IBA
09/2011
1Messenger RNA (mRNA)IBA
09/2011
1Insulin-Like PeptidesIBA
09/2011
1Carrier Proteins (Binding Protein)IBA
09/2011
1denileukin diftitox (Ontak)FDA Link
03/2011
1AutoantigensIBA
05/2006
1LigandsIBA
05/2006
1Glycoproteins (Glycoprotein)IBA
01/2006
1Insulin-Like Growth Factor II (Somatomedin A)IBA
05/2005
1MonokinesIBA
03/2005
1N-(2-acetamido)-2-aminoethanesulfonic acid (ACES)IBA
11/2004
1Immunodominant EpitopesIBA
11/2004
1Immunoglobulin FragmentsIBA
10/2004
1Histocompatibility Antigens Class IIBA
10/2004
1ImmunosorbentsIBA
03/2004
1Hepatitis B Surface Antigens (HBsAg)FDA Link
03/2004
1Hepatitis B e AntigensIBA
03/2004
1EnzymesIBA
03/2004
1Amino AcidsFDA Link
12/2003
1Interleukin-2 (IL2)IBA
09/2003
1IgE Receptors (Fc epsilon RI)IBA
08/2003
1Dextrans (Dextran)FDA Link
07/2003
1Estradiol (Delestrogen)FDA LinkGeneric
07/2003
1Estrogens (Estrogen)FDA Link
07/2003
1Charcoal (Charbon)IBA
07/2003
1ProgesteroneFDA LinkGeneric
07/2003
1Interleukin-10 (Interleukin 10)IBA
05/2003
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2003
1HLA-DR Antigens (HLA-DR)IBA
01/2002
1HER-2-derived peptide 884-899IBA
01/2002
1HLA-DR4 Antigen (HLA DR4 Antigen)IBA
01/2002

Therapy/Procedure

23Immunotherapy
10/2018 - 04/2002
10Therapeutics
06/2020 - 03/2004
4Drug Therapy (Chemotherapy)
01/2014 - 05/2007
2Transplantation
03/2007 - 07/2005
2Injections
03/2005 - 11/2004
1Biological Therapy
09/2012
1Stem Cell Transplantation
03/2007
1Microspheres (Microsphere)
09/2005